In Moosend, you can set multiple segmentation criteria, and narrow down the list of recipients contained inside your segment. This way you can send fully targeted campaigns to the people most likely to respond positively to one of them.
During the creation of a list segment, you must match the segment to your contacts by choosing which of your subscribers has to match the fetch criteria you set. Then you can add one or more rules to define the conditions for your segments.
To learn more about adding segmentation criteria, you can see a concrete example in create a segment out of recipients who haven't opened a specific email campaign.